November 27, 2018

Iodine Tablets. CC BY-NC by Arenamontanus

Investigations reporting low levels of important nutrients to be present in cases of autism are no new thing. Whether this means issues with the availability of certain vitamins or minerals necessary to avoid diseases of deficiency such as scurvy or rickets or just lower levels of nutrients required for optimal biological functioning, the research literature is quite voluminous in this area.

The causes of such deficiencies are still the topic of some research speculation although thought probably partly due to various feeding and dietary issues reported as present in some people with autism and potentially, other biological mechanisms.

A recent paper by Rasha Hamza and colleagues* adds to the discussion in this area, observing that within a small cohort of mothers of children with autism and their offspring, over half of study participants were iodine deficient.

Based on an analysis of Egyptian participants, findings for children with autism and their mothers found that 54% and 58% respectfully were deficient in iodine and further, levels of iodine were negatively associated with severity of autism in children as measured by the Childhood Autism Rating Scale (CARS). The levels of deficiency reported contrasted with no cases of iodine deficiency reported for a control group also studied at the same time.

Iodine is an important mineral for biological functioning due to the body’s requirement for iodine to manufacture thyroid hormones. Thyroid hormones regulate various processes throughout the body including how dietary protein, fats and carbohydrates are used. Thyroid hormones also serve important functions for the developing foetus with deficiency being linked to various developmental and neurodevelopment outcomes for infants. Varying levels of thyroid hormones have also been previously linked to cases of autism.

Whilst the Hamza study was a relatively small investigation looking at a very specific geographical population and also only providing a snapshot of iodine levels and CARS scores at the time of study, there is potentially more to be done in this area with a focus on the link between iodine levels and thyroid functioning in relation to autism. Further, whether supplementation may also have knock-on effects for the presentation of the condition.

* Hamza RT. et al. Iodine Deficiency in Egyptian Autistic Children and Their Mothers: Relation to Disease Severity. Arch Med Res. 2013 Oct 9. pii: S0188-4409(13)00222-1.

Further commentary on this study can be found at: http://questioning-answers.blogspot.co.uk/2013/11/iodine-deficiency-and-autism.html

About the author 

Paul Whiteley Ph.D.

Researcher based in North East England. An academic background in psychology with a special interest in developmental psychology focused specifically on the autism spectrum and related conditions. Postgraduate degrees based on research examining the safety and efficacy of a gluten- and casein-free (GFCF) diet applied to autism and the potential importance of various comorbidity to the health and wellbeing of those on the autism spectrum, with a continuing research interest in these areas. Keen blogger and amateur science writer (but no formal qualifications in these areas). Science is based on probability.

{"email":"Email address invalid","url":"Website address invalid","required":"Required field missing"}

RELATED POSTS

December 24, 2020

From YouTube The United States Senate unanimously passed

November 6, 2020

Liver transplant potentially helpful in rare form of

October 6, 2020

New research conducted by a group of occupational

September 23, 2020

Pain may predict sleeping problems in teens diagnosed

July 15, 2020

A study published in The American Journal of

July 11, 2020

This is part 2 of our review of

June 22, 2020

It may seem like a pipe dream: a

June 4, 2020

CC BY by NIAID The results reported by

June 2, 2020

  On February 2, Autism Daily Newscast reported

>